antisense theory
It is estimated that cancer affects three out of four families in the United States alone the disease and its treatments cause substantial mortality and morbidity, prompting intense interest in cancer prevention. Most available treatments for cancers are non-specific; meaning that they target all rapidly growing cells, both normal and cancerous. Consequences of these treatments include side effects towards the normal cells. In addition, cancer is a genetically unstable disease. Cancer cells can develop drug …
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…a sequence specific, antisense manner to target a gene that is over expressed in cancer or leukemia cells, gene expression can be inhibited and cell growth can be terminated. The application of this theory offers the potential to halt the growth of cancer cells if the over expressed gene can be targeted. The hopes for the future include studying other cell types for similar effects by targeting different over expressed genes using different antisense oligonucleotide.
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