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YELLOW FEVER Yellow fever is a viral disease that has caused large epidemics in Africa and the Americas. It can be recognized from historic texts stretching back 400 years. Infection causes a wide spectrum of disease, from mild symptoms to severe illness and death. The "yellow" in the name is explained by the jaundice that affects some patients. Although an effective vaccine has been available for 60 years, the number of people infected over the last two …

…The British were repeatedly stung by the disease in the Caribbean and South America. In 1741, during an expedition to capture Peru and Mexico, British forces were reduced from 27,000 to 7,000 by the dreaded disease they called "black vomit." Coastal towns and hamlets in the United States were particularly vulnerable to the disease in the seventeenth and eighteenth centuries. Even as late as 1878, a yellow fever epidemic struck more than 100 United States towns, killing at least 20,000 people.