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Sickle-cell anemia also called sickle-cell disease is a hereditary disorder affecting hemoglobin, which is the oxygen carrying substance in red blood cells. This disease ends up decreasing the ability of the hemoglobin to send oxygen throughout the body. The sickle cells begin to clog up the blood vessels which tend to cause inflammation. Sickle-cell anemia relates to me because my cousin Kenny died from this fatal disease. When he died my family greatly changed. In …

…and may pass it on to their siblings. When a person inherits two abnormal HbS genes from each parent, they have sickle-cell disease and will start to show symptoms. The first crises usually start in the early childhood. Crises are critical illnesses. Crises may be carried on by respiratory infection. At this point, the body will really need oxygen. This may cause fever and sharp, intense pain in the back, adomen, chest, arms, and legs.