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In the novel, "Of Mice and Men", many examples of Loneliness and friendship are present. The structure of the novel is based around these sorts of relationships, which are seen all through the book and form the basis of it. Friendships in the novel are far and few between. On the surface it may seem there are many friendships on the ranch, but most of them are superficial. The only true friendship in the book …

…a close, and it is the beginning of the end for this lonely man. As we can see, there were instances of both friendship and loneliness on the ranch. In this unfriendly, selfish place, it truly is a wonder to see how men can pull themselves together under the toughest of conditions, and become friends. But for the others, the ranch was a place of loneliness, in which they knew they could not escape from.