Modeling of Water Uptake
Modeling of Water Uptake into Polymeric Aerosol Particulates Deposited on the Lung Surface
Neil Gupta
Biological Transport
December 12, 2001
Abstract
Inhalation of aerosolized drugs holds promise as a means to treat localized disease states within the lung and may also represent an ideal method for drug delivery to the systemic circulation. The use of polymer-based aerosol carriers for controlled drug delivery via the lung is an approach that may improve the duration and effectiveness of drugs
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from n=1 to 100
Cs=(Cs+(-1)^(n+1)/(n+1)*sin((n+1)*pi*s(j))*exp(-(n+1)^2*pi^2*O(i)));
end
C(i,j)=(2/(pi*s(j))*Cs+1)*(Cinf-Co)+Co; %final concentration as a function of r and t
end
end
%plot(r,C(100,1:1:rnum))
for h=1:10:tnum
plot(r,C(h,1:1:rnum)) %plot C as a function of r at various t
xlabel('Radius (microns)')
ylabel('Water Concentration (mol/L)')
hold on
end
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