Chromosome Probes
Chromosome Probes
Sensitive chromosome probes recently discovered by a University of Toronto
geneticist will make it easier to detect certain types of genetic and prenatal diseases, as
well as being used to determine paternity and provide forensic evidence in criminal
cases.
Probes are short pieces of DNA which bind to, and actually pinpoint, particular
sites on a chromosome. Because these new probes are actually repeated hundreds or
thousands of time at a particular site, they
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in rape or murder cases. "We haven't yet done the analysis
which confirms that our probes are DNA fingerprints, but once we do, we will make
them available for development into tests."
As research progresses in all these areas, Willard hopes to collaborate with other
departments at the U of T to conduct clinical trials. His work is funded by the March of
Dimes, the Hospital for Sick Children Foundation and the Medical Research Council.
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