The Control and Treatment of Chagas’ Disease
Introduction:
Chagas’ disease currently affects 16 million people and 100 million people are thought to be at risk of contracting the disease. Of these 16 million people, 30% will develop debilitating lesions that characterise the incurable form of the disease. It is responsible for an economic loss to the endemic countries of South America of at least £4 billion/year. This type of economical loss combined with the financial benefits of effective control means that trypanosomiasis control is very high …
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…requiring weekly/monthly checks.
The Future?
Some scientists think that the hypoxanthine phosphoribosyltranferase (HPRT) is a possible new site for antiparasite chemotherapy. The crystal structure of HPRT reveals a well-defined target useful in discovering new drugs against T. cruzi. [11]
For other research please refer to The Future when considering Controlling Transmission of the disease.
Conclusions:
In my opinion all transfusions apart from congenital and via vector should be eradicated by the end of the decade.
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