Stereochemistry Considerations
Stereochemistry Considerations
What would you think if I gave you a drug and said this is going to help you but I want you to know ahead of time that 50% of the dose is not affected, in fact the drug is 50% not pure. The idea of that would make you feel you want another drug. The reality of that is that a large # of drugs we give are 50% impure and the reason is b/c …
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…the RR, SS, RS, SR isomers.
What you will notice is that if you look at the alpha 1 activity the SR isomer is the most potent. If you look at the beta 1 activity you can see that the RR isomer is the most potent and if we look at beta 2 activity the RR isomer is also the most potent there. So here we have multiple activities of the drug with different potencies with different isomers.
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